Janumet 50/1000mg Tablet

Description

Product Description
Sitagliptin (DPP4 inhibitors) and Metformin (Biguanides) are combined as Janumet 50 mg/1000 mg Tablet, an anti-diabetic medication used to treat type II diabetes. Type 2 diabetes is characterised by either insufficient insulin production by the body or resistance to the effects of insulin, the hormone that lowers blood sugar levels. Because of this, the body produces a lot of insulin, yet it is unable to affect the organs.

Sitagliptin is a member of the dipeptidyl peptidase-4 (DPP-4) inhibitor class, which lowers high blood sugar by boosting the levels of specific natural chemicals. Metformin is another medication that reduces the liver’s generation of glucose, delays the intestines’ absorption of glucose, and makes the body more sensitive to insulin. It is a member of the biguanide class. Therefore, following meals, Janumet 50 mg/1000 mg Tablet prevents blood glucose levels from increasing to extremely high levels.

To prevent an upset stomach, Janumet 50 mg/1000 mg Tablets should be taken with food. For optimal effects, Janumet 50 mg/1000 mg Tablets should be taken consistently at the same time of day. For better guidance, your doctor will determine the appropriate dosage, which may vary over time based on your health. Hypoglycemia (low blood glucose levels) is the most frequent adverse effect of Janumet 50 mg/1000 mg tablets. It is marked by symptoms such as dry mouth and skin, palpitations, sweating, and dizziness. Therefore, you should always have some sort of sugar on hand and avoid skipping meals in order to prevent hypoglycemia. Changes in taste, nausea, diarrhoea, headaches, stomachaches, and upper respiratory problems are additional adverse effects.

Even if you feel better, you should not stop taking Janumet 50 mg/1000 mg tablets without first talking to your doctor because your blood sugar levels are constantly fluctuating. Abruptly stopping Janumet 50 mg/1000 mg Tablets may raise your blood sugar levels, which may further raise your chance of developing retinopathy, nephropathy, and neuropathy. If you have severe kidney or liver illness or type 1 diabetes mellitus, you should not take Janumet 50 mg/1000 mg tablets. If you have heart problems of any kind, are pregnant, or are nursing, please let your doctor know.

Medicinal Benefits
The Janumet 50 mg/1000 mg Tablet reduces the extra sugar the liver produces, increases the amount of insulin the pancreas produces, and helps the body use insulin efficiently. It aids in regulating the post-meal spike in blood sugar levels. In addition, long-term use does not result in weight increase. The Janumet 50 mg/1000 mg Tablet is essential for blood sugar regulation. It avoids major problems from diabetes, such as diabetic foot ulcers, delayed wound healing, kidney damage (nephropathy), nerve damage (neuropathy), and vision loss (retinopathy).

Instructions for Use
Consume Janumet 50 mg or 1000 mg tablets as directed by your physician. Don’t chew, break, or crush it; instead, swallow it whole with water.

Storage
Store in a cool and dry place away from sunlight

Janumet 50 mg/1000 mg Tablet Side Effects
•Low blood sugar
•Runny nose
•Sore throat
•Upper lung infection
•Diarrhoea
•Nausea
•Vomiting
•Gas
•Stomach upset
•Indigestion
•General weakness
•Headache

Warnings About Drugs
Patients with type 1 diabetes or diabetic ketoacidosis should not take Janumet 50 mg/1000 mg tablets. When taking Janumet 50 mg/1000 mg tablets, certain diabetic individuals may get lactic acidosis, an uncommon but dangerous illness. Too much lactic acid builds up in the blood in this disease, which can harm the kidneys and liver, which are necessary to remove too much lactic acid from the blood. Inform your doctor if you have ever experienced kidney illness, low vitamin B12 levels, or pancreatitis (inflammation of the pancreas) before beginning to take Janumet 50 mg/1000 mg tablets.

When used with insulin, Janumet 50 mg/1000 mg Tablet may cause hypoglycemia, which can be extremely dangerous. Your doctor might lower the insulin dosage or Janumet 50 mg/1000 mg tablet in this situation. An annual TSH checkup is advised since prolonged use of Janumet 50 mg/1000 mg Tablets may decrease your thyroid-stimulating hormone (TSH). Rarely, you can also get bullous pemphigoid, a severe skin response that needs to be treated right away. If a dye injection or X-ray contrast agent will be used during a diagnostic test, let your doctor know. A brief cessation of Janumet 50 mg/1000 mg Tablet use is advised before to an X-ray procedure.

Interactions with Drugs
Antidepressants (bupropion), glaucoma medications, antibiotics (cephalexin, ciprofloxacin), anti-acidity medications (cimetidine), heart condition medications (digoxin), anti-HIV medications (dolutegravir), ethanol, saliva reducing medications (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic medications (topiramate, lamotrigine), and heart-related chest medications (ranolazine) are among the medications that interact with Janumet 50 mg/1000 mg tablets. Additional drug interactions, such as those involving sex hormones (androgens), antioxidants (alpha-lipoic acid), pain relievers (aspirin), anti-TB medications (prothionamide), growth hormones (pegvisomant), and other antidiabetic medications, might also result in elevated low blood sugar.

Drug-Food Interactions: Drinking too much alcohol can raise your risk of developing lactic acidosis, a potentially fatal illness. Therefore, refrain from drinking alcohol when taking Janumet 50 mg/1000 mg tablets.

Drug-Disease Interactions: Janumet 50 mg/1000 mg Tablet should not be taken by those who have heart conditions (such as congestive heart failure and myocardial infarction), a vitamin B12 deficiency, or an alcohol addiction.

Advice on Diet and Lifestyle
•Consume whole grains, proteins, and starchy vegetables.
•Eat at regular intervals. Avoid going too long between meals or snacks.
•Regularly check your blood sugar level.
•Eat sugar sweets or sip sugary drinks right away if you feel as though your blood sugar is dropping and you are becoming weak. It will assist in bringing your body’s blood sugar levels into balance. Therefore, it’s a good idea to carry sugar candy.
•Every week, dedicate at least 150 minutes to moderate-intensity exercise or an hour and fifteen minutes to high-intensity exercise.
•To reach a healthy body mass index (18.5 to 24.9), progressively reduce your weight.
•Consume more fruits, vegetables, and other foods high in fibre and swap out items high in refined carbohydrates with whole grain foods.
•Cut back on foods like chips, crisps, pastries, biscuits, and samosas that contain saturated fat, often known as hidden fats. For everyday cooking, use oils that contain omega-3 fatty acids. Palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil can all be used for frying.
•Avoid stress since it can cause your blood sugar to rise. To regulate blood sugar fluctuations brought on by stress, you can use stress-reduction strategies like mindfulness.
•Choose dairy items that are low in fat, such as cheese, fat-free milk, and low-fat yoghurt.
•Maintain your blood pressure as close to normal as you can (140/90). because it lowers diabetics’ risk of cardiovascular illnesses.

Glossary of Conditions and Diseases
The condition known as type 2 diabetes occurs when the body is unable to produce enough insulin or when the insulin it does produce is not efficiently utilised by the body. Hyperglycemia, or elevated blood sugar, may result from this. Increased thirst, nighttime urination, sluggish wound healing, increased appetite, exhaustion, and blurred vision are all signs of type 2 diabetes. Weight loss may be seen in rare instances, whereas weight increase may occur in other situations. In addition, retinopathy (damaged retina of eyes or blindness), nephropathy (kidney problems), neuropathy (nerve problems), loss of limbs, sexual dysfunction, and an increased risk of heart attack or stroke are complications of type 2 diabetes.