Istamet 50mg/500mg Tablet

Description

Product Description
Sitagliptin (DPP4 inhibitors) and Metformin (Biguanides) are combined as the medication Istamet 50 mg/500 mg Tablet, which is an anti-diabetic medication used to treat type II diabetes. Type 2 diabetes is characterised by either insufficient insulin production by the body or resistance to the effects of insulin, the hormone that lowers blood sugar levels. Because of this, the body produces a lot of insulin, yet it is unable to affect the organs.

Sitagliptin is a member of the dipeptidyl peptidase-4 (DPP-4) inhibitor class, which lowers high blood sugar by boosting the levels of specific natural chemicals. Metformin is another medication that reduces the liver’s generation of glucose, delays the intestines’ absorption of glucose, and makes the body more sensitive to insulin. It is a member of the biguanide class. Therefore, following meals, Istamet 50 mg/500 mg Tablet prevents blood glucose levels from increasing to extremely high levels.

To prevent an upset stomach, take the 50 mg/500 mg Istamet tablet with food. For optimal effects, the 50 mg/500 mg Istamet Tablet should always be taken at the same time of day. For better guidance, your doctor will determine the appropriate dosage, which may vary over time based on your health. Hypoglycemia (low blood glucose levels) is the most frequent adverse effect of Istamet 50 mg/500 mg Tablets. It is marked by symptoms such as dry mouth and skin, palpitations, perspiration, and dizziness. Therefore, you should always have some sort of sugar on hand and avoid skipping meals in order to prevent hypoglycemia. Changes in taste, nausea, diarrhoea, headaches, stomachaches, and upper respiratory problems are additional adverse effects.

Istamet 50 mg/500 mg Tablet should not be stopped even if you feel better, without consulting the doctor as your sugar level keeps changing. If you stop taking Istamet 50 mg/500 mg Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Istamet 50 mg/500 mg Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, are planning to get pregnant or are breastfeeding.

Medicinal Benefits
The 50 mg/500 mg tablet of Istamet aids in the production of more insulin by the pancreas, its efficient use, and the reduction of excess sugar produced by the liver. It aids in regulating the post-meal spike in blood sugar levels. In addition, long-term use does not result in weight increase. The 50 mg/500 mg tablet of Istamet is essential for blood sugar regulation. It avoids major problems from diabetes, such as diabetic foot ulcers, delayed wound healing, kidney damage (nephropathy), nerve damage (neuropathy), and vision loss (retinopathy).

Directions for Use
Take the 50 mg or 500 mg Istamet tablet as directed by your physician. Don’t chew, break, or crush it; instead, swallow it whole with water

Storage
Store in a cool and dry place away from sunlight.

Side Effects of Istamet 50 mg/500 mg Tablet
•Low blood sugar
•Runny nose
•Sore throat
•Upper lung infection
•Diarrhoea
•Nausea
•Vomiting
•Gas
•Stomach upset
•Indigestion
•General weakness
•Headache 
  
Warnings About Drug
Patients with diabetic ketoacidosis or type 1 diabetes should not take Istamet 50 mg/500 mg tablets. When taking 50 mg or 500 mg tablets of Istamet, certain diabetic patients may have lactic acidosis, a rare but dangerous disease. Too much lactic acid builds up in the blood in this disease, which can harm the kidneys and liver, which are necessary to remove too much lactic acid from the blood. Inform your doctor if you have ever experienced renal illness, low vitamin B12 levels, or pancreatitis (inflammation of the pancreas) before beginning to take Istamet 50 mg/500 mg Tablet. When used with insulin, Istamet 50 mg/500 mg Tablet may cause hypoglycemia, a potentially dangerous condition that lowers blood sugar levels. Your doctor might lower the insulin dosage or the Istamet 50 mg/500 mg tablet in this situation.

It is advised to get your thyroid-stimulating hormone (TSH) checked annually because prolonged use of Istamet 50 mg/500 mg Tablets may cause your TSH levels to drop. Rarely, you can also get bullous pemphigoid, a severe skin response that needs to be treated right away. If a dye injection or X-ray contrast agent will be used during a diagnostic test, let your doctor know. A brief cessation of Istamet 50 mg/500 mg Tablet use is advised before to an X-ray procedure.

Interactions with Drug
Drug-Drug Interactions: ethanol, saliva-reducing medications (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic medications (topiramate, lamotrigine), an antidepressant (bupropion), medications for glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity medications (cimetidine), heart condition medications (digoxin), anti-HIV medications (dolutegravir), and medications for heart-related chest conditions (ranolazine). Additional drug interactions, such as those involving sex hormones (androgens), antioxidants (alpha-lipoic acid), pain relievers (aspirin), anti-TB medications (prothionamide), growth hormones (pegvisomant), and other antidiabetic medications, might also result in elevated low blood sugar.

Drug-Food Interactions: Drinking too much alcohol can raise your risk of developing lactic acidosis, a potentially fatal illness. Therefore, refrain from drinking alcohol when taking 50 mg or 500 mg tablets of Istamet.

Drug-Disease Interactions: Istamet 50 mg/500 mg Tablet should not be taken by those who have heart conditions (such as congestive heart failure and myocardial infarction), a vitamin B12 deficiency, or an alcohol addiction.

Advice on Diet and Lifestyle
•Consume whole grains, proteins, and starchy vegetables.
•Eat at regular intervals. Avoid going too long between meals or snacks.
•Regularly check your blood sugar level.
•Eat sugar sweets or sip sugary drinks right away if you feel as though your blood sugar is dropping and you are becoming weak. It will  assist in bringing your body’s blood sugar levels into balance. Therefore, it’s a good idea to carry sugar candy.
•Every week, dedicate at least 150 minutes to moderate-intensity exercise or an hour and fifteen minutes to high-intensity exercise.
•Cut back on foods like chips, crisps, pastries, biscuits, and samosas that contain saturated fat, often known as hidden fats. For everyday cooking, use oils that contain omega-3 fatty acids. Palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil can all be used for frying.
•Avoid stress since it can cause your blood sugar to rise. To regulate blood sugar fluctuations brought on by stress, you can use stress-reduction strategies like mindfulness.
•Choose dairy items that are low in fat, such as cheese, fat-free milk, and low-fat yoghurt.
Maintain your blood pressure as close to normal as you can (140/90). because it lowers diabetics’ risk of cardiovascular illnesses.

Glossary of Conditions and Diseases
The condition known as type 2 diabetes occurs when the body is unable to produce enough insulin or when the insulin it does produce is not efficiently utilised by the body. Hyperglycemia, or elevated blood sugar, may result from this. Increased thirst, nighttime urination, sluggish wound healing, increased appetite, exhaustion, and blurred vision are all signs of type 2 diabetes. Weight loss may be seen in rare instances, whereas weight increase may occur in other situations. In addition, retinopathy (damaged retina of eyes or blindness), nephropathy (kidney problems), neuropathy (nerve problems), loss of limbs, sexual dysfunction, and an increased risk of heart attack or stroke are complications of type 2 diabetes.